Around 317 miles of Route 66 wind through Missouri, the fifth longest stretch out of the eight states on your Mother Road journey. Starting at the Old Chain of Rocks Bridge that crosses the Mississippi River from Illinois into St. Louis and ending at the Kansas state line, just west of Joplin, there are quintessential Missouri Route 66 attractions to see at every turn of the road.
You’ll find quirky roadside attractions, historical museums, vintage diners and drive-throughs, fun souvenir shops, and classic motels and hotels on this stretch of your road trip.
Looking for the best Missouri Route 66 attractions to add to your road trip itinerary? Use the filters below to search our Missouri directory by location, attraction type, or keyword to fill your travel plan, whether you’re spending a weekend in Springfield, taking a day trip from St. Louis, or traversing all 317 miles of The Main Street of America across the state.
Find something you like? Tap “Save to My Trip” to create your own customized Route 66 itinerary!
Search Missouri Route 66 Attractions
Found 101 Results
Page 3 of 11
The European in Springfield, Missouri
The European is a cafe on Park Central Square in Springfield, Missouri, serving breakfast, lunch, pastries, and espresso drinks in a historic setting. It focuses on scratch-made dishes alongside a full coffee menu with both classic and specialty drinks.
Black Sheep Burgers & Shakes in Springfield, Missouri
Black Sheep Burgers & Shakes is a casual restaurant in Springfield, Missouri, known for its gourmet burgers, loaded fries, and milkshakes. Opened in 2015, it features a rock-and-roll-themed interior and a menu built around Wagyu beef burgers with creative toppings, along with shareable fry options and a variety of dipping sauces.
Mother’s Brewing Company in Springfield, Missouri
Mother’s Brewing Company is the largest craft brewery in Springfield, Missouri, located just off Route 66 in a former bakery building. Open since 2011, it offers a rotating selection of house-made beers, cider, and cocktails in a taproom with indoor seating and an outdoor lawn.
The Golden Girl Rum Club in Springfield, Missouri
The Golden Girl Rum Club is a tropical-themed bar on Park Central Square in downtown Springfield, Missouri, known for its retro-inspired atmosphere and extensive rum selection. The menu includes scratch-made cocktails, including both tropical drinks and classics, along with a small food menu featuring tacos, rice bowls, and specialty pizzas.
Trailer Perk Coffee in Springfield, Missouri
Trailer Perk Coffee is a retro-styled drive-through spot on Route 66 in Springfield, Missouri, known for its bold colors, neon sign, and a flamingo mascot greeting you at the lane. The menu features creative, house-made drinks like the Route 66 Kicker and toasted marshmallow mochas, alongside classic coffee options.
Civil Kitchen in Springfield, Missouri
Civil Kitchen offers a fresh take on comfort food along Route 66 in Springfield, Missouri, blending Southern and Midwestern flavors with creative twists on familiar favorites. Scratch-made dishes like chicken and waffles, seafood beignets, and inventive tacos keep things interesting, while a strong lineup of drinks rounds out the experience.
Must SeeBirthplace of Route 66 Monument in Springfield, Missouri
The Birthplace of Route 66 Monument in Jubilee Park, just off Park Central Square in Springfield, Missouri, features a large black-and-white Route 66 shield with cutouts in the two sixes so visitors can climb in for a commemorative photo, topped with a bold red banner reading "BIRTHPLACE OF ROUTE 66."
Cunningham Park Tornado Memorial in Joplin, Missouri
On May 22, 2011, an EF-5 tornado tore through Joplin, Missouri, leaving a 13.8-mile path of destruction up to a mile wide. It was one of the deadliest tornadoes in U.S. history, claiming 161 lives and destroying large parts of the city, including neighborhoods, schools, and Cunningham Park.
Grand Falls in Joplin, Missouri
Just a stone’s throw from downtown Joplin (and not far off the historic Mother Road) Grand Falls offers a natural detour worth pulling over for. As Missouri’s largest continuously flowing natural waterfall, this scenic spot on Shoal Creek drops 12 feet over a 163-foot-wide ledge of solid chert.
Jasper County Courthouse in Carthage, Missouri
Just a few blocks from Route 66, right in the heart of the Carthage town square, you’ll find one of Missouri’s most striking landmarks: the Jasper County Courthouse. Built between 1894 and 1895, this towering Romanesque Revival-style courthouse was designed by architect Max A. Orlopp Jr. and constructed using locally sourced Carthage stone.
Lost Along the Mother Road
Not every stop along Route 66 has stood the test of time. Over the decades, some Route 66 attractions have faded from the map, leaving behind ghost towns, relics, and memories of what once was. These sites may be gone, but they are not forgotten, living on through photos, memories, and the travelers who still seek their traces.
