Around 317 miles of Route 66 wind through Missouri, the fifth longest stretch out of the eight states on your Mother Road journey. Starting at the Old Chain of Rocks Bridge that crosses the Mississippi River from Illinois into St. Louis and ending at the Kansas state line, just west of Joplin, there are quintessential Missouri Route 66 attractions to see at every turn of the road.
You’ll find quirky roadside attractions, historical museums, vintage diners and drive-throughs, fun souvenir shops, and classic motels and hotels on this stretch of your road trip.
Looking for the best Missouri Route 66 attractions to add to your road trip itinerary? Use the filters below to search our Missouri directory by location, attraction type, or keyword to fill your travel plan, whether you’re spending a weekend in Springfield, taking a day trip from St. Louis, or traversing all 317 miles of The Main Street of America across the state.
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Big Route 66 Shield in Waynesville, Missouri
The Big Route 66 Shield in Waynesville, Missouri was installed in August 2020. This massive 8-by-8-foot sign weighs over 1,000 pounds and proudly pays tribute to the legacy of the Mother Road. The idea for the giant shield was sparked by Tim Berrier of Lone Oak Printing.
Lost Along the Mother Road
Not every stop along Route 66 has stood the test of time. Over the decades, some Route 66 attractions have faded from the map, leaving behind ghost towns, relics, and memories of what once was. These sites may be gone, but they are not forgotten, living on through photos, memories, and the travelers who still seek their traces.
