Missouri Route 66 Attractions

Around 317 miles of Route 66 wind through Missouri, the fifth longest stretch out of the eight states on your Mother Road journey. Starting at the Old Chain of Rocks Bridge that crosses the Mississippi River from Illinois into St. Louis and ending at the Kansas state line, just west of Joplin, there are quintessential Missouri Route 66 attractions to see at every turn of the road.

You’ll find quirky roadside attractions, historical museums, vintage diners and drive-throughs, fun souvenir shops, and classic motels and hotels on this stretch of your road trip.

Looking for the best Missouri Route 66 attractions to add to your road trip itinerary? Use the filters below to search our Missouri directory by location, attraction type, or keyword to fill your travel plan, whether you’re spending a weekend in Springfield, taking a day trip from St. Louis, or traversing all 317 miles of The Main Street of America across the state.

Find something you like? Tap “Save to My Trip” to create your own customized Route 66 itinerary!

Search Missouri Route 66 Attractions

Found 21 Results

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Red Oak Diner at Red Oak II in Carthage, Missouri Route 66 Roadside Attraction

Red Oak II, Missoura in Carthage, Missouri

Red Oak II, Missoura in Carthage, Missouri is seemingly a ghost town, but actually is so much more. It is an open-air museum, historical landmark, art project, and roadside attraction in one. Located just off of Route 66 it’s a must-see road trip stop. Red Oak II was the vision of artist Lowell Davis. Davis…


Missouri Hick Bar-B-Que in Cuba, Missouri Route 66 Restaurant

Missouri Hick Bar-B-Que in Cuba, Missouri

Missouri Hick Bar-B-Que in Cuba, Missouri offers a fun stop with delicious food right on Route 66. Missouri Hick is the brainchild of master barbecuer and woodworker Dennis Meiser, whose handcrafted touch is apparent in everything from the pork to the portico. He opened the restaurant in 2002, serving delicious food to locals and Route…


Red velvet doughnut at Donut Drive-In in St. Louis, Missouri Route 66 Doughnut Shop

Donut Drive-In in St. Louis, Missouri

DONUT miss this stop on your Route 66 road trip through Missouri. Donut Drive-In in St. Louis is a beloved institution for both locals and travelers alike. Opened in 1953, Donut Drive-In retains much of its original charm and many original 1950s recipes. Stop into the small shop for a handmade apple fritter, long john,…


Hubble Telescope Replica Statue in Marshfield, Missouri Route 66 Roadside Attraction

Hubble Telescope Replica Statue in Marshfield, Missouri

The Hubble Space Telescope is one of the largest space telescopes ever launched by NASA. It's remained in operation since 1990 and is maintained in space by astronauts. The Hubble Telescope Replica Statue in Marshfield, Missouri isn't quite as big, at 1/4 the size of the real thing, but it is much more accessible attraction…


Beaver Statue in front of the Route 66 Buc-ee's in Springfield, Missouri

Buc-ee’s in Springfield, Missouri

Need gas, snacks, or souvenirs on your Route 66 road trip? Springfield, Missouri is home to the very first Buc-ee's in Missouri. The popular travel center and road trip stop has made a home in the "Birthplace of Route 66." Buc-ee's is a popular chain of travel centers that was founded in Lake Jackson, Texas…


Chef Muffler Man in Springfield, Missouri Route 66 Roadside Attraction

Chef Muffler Man in Springfield, Missouri

The Route 66 Food Truck Park opened in Springfield, Missouri in February 2020. The spot featured food trucks with a variety of different cuisines, a full-service bar, and this giant Chef Muffler Man, affectionally named Carl, out front. This is one of the many muffler man roadside attractions on Route 66. Muffler Men are fiberglass…


Mega Mayor Muffler Man in St Roberts, Missouri Route 66 roadside attraction

Uranus Mega Mayor Muffler Man in St. Robert, Missouri

What do you do when you already own one of the weirdest stops on Route 66? Add more weird! And what better way to do that than by adding a muffler man roadside attraction. Better yet, a custom made muffler man modeled after yourself. Find the Mega Mayor Muffler Man in St. Robert, Missouri, just…


Red’s Giant Hamburg in Springfield, Missouri Route 66 Drive In Restaurant

Red’s Giant Hamburg in Springfield, Missouri

Red’s Giant Hamburg in Springfield, Missouri first opened its doors on Route 66 in 1947. The tiny restaurant was run by Sheldon “Red” Chaney (May 20, 1916 – June 2, 1997) and was located in a former Sinclair gas station. It had one unique feature never seen before: a drive-though window. The restaurant was allegedly…


Birthplace of Route 66 Roadside Park in Springfield, Missouri Route 66 Roadside Attraction

Birthplace of Route 66 Roadside Park in Springfield, Missouri

Springfield, Missouri is officially recognized as the birthplace of Route 66. It was via telegram at a 1926 meeting of highway officials at the Colonial Hotel that Springfield businessman John T. Woodruff and Oklahoma businessman Cyrus Avery first proposed U.S. 66 as the name of the new Chicago-to-Los Angeles highway. The Birthplace of Route 66…


Best Western Route 66 Rail Haven Motel in Springfield, Missouri Route 66 Motel

Best Western Route 66 Rail Haven Motel in Springfield, Missouri

The Best Western Route 66 Rail Haven Motel in Springfield, Missouri (also known as Rail Haven Motel or Rail Haven Motor Court) was built in 1938 and for many years was a true Route 66 institution that attracted Route 66 travelers and celebrities alike. Today the hotel is operated under the Best Western brand but…


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