Around 317 miles of Route 66 wind through Missouri, the fifth longest stretch out of the eight states on your Mother Road journey. Starting at the Old Chain of Rocks Bridge that crosses the Mississippi River from Illinois into St. Louis and ending at the Kansas state line, just west of Joplin, there are quintessential Missouri Route 66 attractions to see at every turn of the road.
You’ll find quirky roadside attractions, historical museums, vintage diners and drive-throughs, fun souvenir shops, and classic motels and hotels on this stretch of your road trip.
Looking for the best Missouri Route 66 attractions to add to your road trip itinerary? Use the filters below to search our Missouri directory by location, attraction type, or keyword to fill your travel plan, whether you’re spending a weekend in Springfield, taking a day trip from St. Louis, or traversing all 317 miles of The Main Street of America across the state.
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Search Missouri Route 66 Attractions
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Must SeeMunger Moss Motel in Lebanon, Missouri
The Munger Moss Motel in Lebanon, Missouri was built in 1946 and you can still spend the night at this classic Route 66 motel on your road trip. The site originally operated as a filling station and restaurant and the motel was added on after the business relocated, though it is the only part that has survived today.
Frisco’s Train and Cowcatcher Seat in Cuba, Missouri
Check out Frisco's Train and Cowcatcher Seat outside Frisco’s Grill and Pub in Cuba, Missouri. This impressive steam engine replica appears to emerge right out of a tunnel at the side of Frisco’s. Up front, you’ll spot a custom cowcatcher bench—a nod to the part of a train that clears obstacles from the track.
Roubidoux Spring at Laughlin Park in Waynesville, Missouri
Roubidoux Spring at Laughlin Park in Waynesville, Missouri is a scenic slice of Ozark beauty that blends natural wonder, cultural history, and a touch of aquatic adventure. Roubidoux Spring is a second-magnitude spring that gushes an average of 37 million gallons of crystal-clear water each day.
Must SeeCollege Street Café in Springfield, Missouri
College Street Cafe in Springfield, Missouri offers comforting meals and friendly hospitality on Route 66. The diner opened in Springfield in the 1950s. Though it went through different names and several owners over the years it always was there to serve hearty meals to Route 66 travelers and locals alike.
Route 66 Museum in Lebanon, Missouri
The Route 66 Museum in Lebanon, Missouri is dedicated to celebrating The Mother Road, with a special spotlight on the local area. Step back in time as you wander through displays and life-sized dioramas, like a 1950s gas station, complete with vintage pumps and a classic car from the era.
Redmon’s Candy Factory in Phillipsburg, Missouri
Make sure to pull over at Redmon’s Candy Factory in Phillipsburg, Missouri, for a sweet break on your Route 66 adventure! Whether you're craving homemade fudge, candy by the pound, popcorn, or a fun soda to keep you refreshed, this place has it all. You can’t miss the bright billboards for Redmon’s Candy Factory.
World’s Largest Gift Store in Phillipsburg, Missouri
Road tripping Missouri and looking for the perfect souvenir stop? Make sure to pull over at the World’s Largest Gift Store in Phillipsburg, Missouri, where you’ll find a huge variety of gifts for your family, friends, or maybe just a little something for yourself. You can’t miss the eye-catching billboards for the World’s Largest Gift Store.
Must SeeRed Oak II, Missoura in Carthage, Missouri
Red Oak II, Missoura in Carthage, Missouri is seemingly a ghost town, but actually is so much more. It is an open-air museum, historical landmark, art project, and roadside attraction in one. Located just off of Route 66 it’s a must-see road trip stop. Red Oak II was the vision of artist Lowell Davis.
Hubble Telescope Replica Statue in Marshfield, Missouri
The Hubble Space Telescope is one of the largest space telescopes ever launched by NASA. It's remained in operation since 1990 and is maintained in space by astronauts. The Hubble Telescope Replica Statue in Marshfield, Missouri isn't quite as big, at 1/4 the size of the real thing, but it is much more accessible attraction for mankind.
Buc-ee’s in Springfield, Missouri
Need gas, snacks, or souvenirs on your Route 66 road trip? Springfield, Missouri is home to the very first Buc-ee's in Missouri. The popular travel center and road trip stop has made a home in the "Birthplace of Route 66." Buc-ee's is a popular chain of travel centers that was founded in Lake Jackson, Texas in 1982.
Lost Along the Mother Road
Not every stop along Route 66 has stood the test of time. Over the decades, some Route 66 attractions have faded from the map, leaving behind ghost towns, relics, and memories of what once was. These sites may be gone, but they are not forgotten, living on through photos, memories, and the travelers who still seek their traces.
